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Activated Folate


Equilibrium Nutrition's Activated Folate is a functional medicine formula containing calcium 5-methyltetrahydrofolate. Folate is the naturally occurring form of vitamin B9 found in many foods. It is also sometimes referred to as methylfolate, methylated folate, methyl folate, or folic acid (the synthetic form).

An essential nutrient, our bodies require folate for many important functions including the formation of DNA, nervous system development and cellular function. Furthermore, the body does not store folate, making regular intake critical. For this reason, supplementation is often recommended including an increased intake for women during pregnancy.

Equilibrium Nutrition's Activated Folate is a functional medicine formula containing calcium 5-methyltetrahydrofolate. Folate is the naturally occurring form of vitamin B9 found in many foods. It is also sometimes referred to as methylfolate, methylated folate, methyl folate, or folic acid (the synthetic form).

An essential nutrient, our bodies require folate for many important functions including the formation of DNA, nervous system development and cellular function. Furthermore, the body does not store folate, making regular intake critical. For this reason, supplementation is often recommended including an increased intake for women during pregnancy.

   


Folates are various forms of vitamin B-9 that are important nutrients for the proper function of the body and brain alike. Unlike fat-soluble vitamins, water-soluble vitamins like folate cannot be stored in the body, making consistent dietary intake necessary and supplementation recommended. While folate is the natural form of vitamin B9 found in a variety of foods, a commonly known alternative, folic acid, is the synthetic form. Synthetic folic acid is the form most often added to fortified foods.

The biologically active form of vitamin B9 is known as levomefolic acid or 5-methyltetrahydrofolate (5-MTHF), which is what we use in our formulation. Most dietary folate is converted into 5-MTHF during digestion before entering your bloodstream. In contrast, not all of the synthetic folic acid is converted by the body into the active form of vitamin B9 (5-MTHF).

Folate is perhaps best known as being required for the healthy development of the fetus during pregnancy, as well as during periods of rapid growth such as infancy and adolescence. However, recent research has also suggested that the father's folate levels before conception may be just as important. (1)

Everyone needs folate as it's essential for many important bodily systems including cellular, cardiovascular, and neurological. While deficiency is rare, folate inadequacy is common in certain populations, such as in pregnant women.

WHAT ARE ACTIVATED B-VITAMINS?

"Activated" refers to the specific type of a B-Vitamin that has already been formulated to be in its more absorbable form. This activated, or "methylated" version means that your body is able to use more of it. It also means that there will not be the same type of potential toxic build-up when you use low quality, non-methylated forms such as folic acid. Equilibrium Nutrition is dedicated to only using the highest level of 3rd-party-tested nutritional supplements that are based on science and proven to work.

FOLATE BENEFITS†

  • Supports DNA Creation and Repair
  • Helps Protect Against Neural Birth Defects
  • Enhances Cardiovascular Function
  • Promotes Brain, Nerve and Organ Function
  • Balances Mood
  • Aids in Digestion
  • Maintains Healthy Hair, Skin and Nails

Cellular and Cardiovascular Health

Folate is important for healthy cell growth and function, including red and white blood cell formation. It is one of several important vitamins involved in cell function and healthy cell growth. It's also responsible for the formation and repair of DNA, RNA and other genetic material and plays an important role in cell division. Folate, along with other B vitamins, is also involved in homocysteine (an amino acid) metabolism. Research has suggested that folate and other B vitamins support cardiovascular health by lowering homocysteine levels which, when high, can affect heart health (2).

Brain and Mood Health

Folate is important for healthy cell growth and function, including red and white blood cell formation. It is one of several important vitamins involved in cell function and healthy cell growth. It's also responsible for the formation and repair of DNA, RNA and other genetic material and plays an important role in cell division. Folate, along with other B vitamins, is also involved in homocysteine (an amino acid) metabolism. Research has suggested that folate and other B vitamins support cardiovascular health by lowering homocysteine levels which, when high, can affect heart health (2).

Prenatal Health

Demands for folate increase during pregnancy because it is required for the growth and healthy development of the fetus. A large body of research has shown that folate supplementation can help prevent complications such as low birth weight and neural tube birth defects (5,6,7).

THE DANGERS OF FOLATE DEFICIENCY†

Although isolated folate deficiency is uncommon, low levels of folate in the body (folate inadequacy) are estimated to affect at least 20% of the US population (8). Those at the greatest risk of deficiency include women of childbearing age, pregnant women, those with high alcohol intake, those with malabsorptive disorders, and those with the genetic MTHFR polymorphism (9).

Although many foods are fortified with folic acid in an effort to minimize folate inadequacy, we all have varying levels of folate intake and metabolism. While some people may be slightly less efficient at processing folate in the body, others may be highly inefficient. Furthermore, it was recently discovered that many people cannot efficiently methylate folic acid due to genetic differences in the MTHFR gene. Fortunately, L-methylfolate (also known as L-5-methyltetrahydrofolate or 5-MTHF) is the biologically active, methylated form of folate that bypasses the MTHFR-dependent methylation step. This is the form of folate we use in our Activated Folate solution.

DIRECTIONS

Take 1 capsule per day or as directed by your healthcare professional. This product is ideally used along with an Activated B-Complex, which includes folate synergistic partners including vitamins B6 and B12.

DOES NOT CONTAIN

Nuts, dairy, soy, gluten, GMOs.

CAUTIONS

Consult your healthcare professional prior to using this product if you are pregnant, nursing, taking medication(s) or have a medical condition.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

 

  1. Lambrot R, Xu C, Saint-Phar S, et al. Low paternal dietary folate alters the mouse sperm epigenome and is associated with negative pregnancy outcomes. Nature Communications. 2013;4(1). doi:10.1038/ncomms3889
  2. Clarke R, Halsey J, Lewington S, et al. Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality: Meta-analysis of 8 randomized trials involving 37 485 individuals. Arch Intern Med. 2010;170(18):1622-1631. doi:10.1001/archinternmed.2010.348
  3. Melong J, Gardner D. Women with depression should be offered folic acid. Can Fam Physician. 2011;57(9):993-996.
  4. Ramanujam B, Bajaj BK, Kaur K, Anand KS, Buxi G. Is Depression Related to Low Folate Levels in People with Epilepsy? An Observational Study and Meta-analysis. J Neurosci Rural Pract. 2017;8(3):381-388. doi:10.4103/jnrp.jnrp_468_16
  5. Obeid R, Holzgreve W, Pietrzik K. Folate supplementation for prevention of congenital heart defects and low birth weight: an update. Cardiovasc Diagn Ther. 2019;9(Suppl 2):S424-S433. doi:10.21037/cdt.2019.02.03
  6. Blom HJ, Smulders Y. Overview of homocysteine and folate metabolism. With special references to cardiovascular disease and neural tube defects. J Inherit Metab Dis. 2011;34(1):75-81. doi:10.1007/s10545-010-9177-4
  7. Kennedy D, Koren G. Identifying women who might benefit from higher doses of folic acid in pregnancy. Can Fam Physician. 2012;58(4):394-397.
  8. Pfeiffer CM, Sternberg MR, Zhang M, et al. Folate status in the US population 20 y after the introduction of folic acid fortification. The American Journal of Clinical Nutrition. 2019;110(5):1088-1097. doi:10.1093/ajcn/nqz184
  9. National Institute of Health. Office of Dietary Supplements (ODS). Folate Fact Sheet for Health Professionals. 2020. Retrieved from https://ods.od.nih.gov/factsheets/Folate-HealthProfessional/#ref
 
 

Family First

Every product on this website was formulated with the mindset that my family and I would be using each nutritional supplement.

When you go into a product formulation knowing that your own family and children will use these products it ensures there will never be any compromise…

Plus, I want only the best for my online community and private practice clients. And, since people come to me for results after failing many times in the past, I have to know that every one of these products are truly the best of the best and will help people on their healing journey…

 

Functional Medicine Formulations

It’s important to understand that not all nutritional supplements are created equal.

For example, in a Functional Medicine practice only methylated or highly bio-available vitamins and minerals will be used in order to make it easy for the body to utilize.

Not only do these formula get better results, but they do not build up as toxins in the body or simply get excreted in the urine like most cheaper forms… 

 

Zero Compromise Policy

I made a promise to myself when I first started formulating the Equilibrium Nutrition line that I would not compromise on quality…

Even if a product cost me a few more dollars, I would not take any shortcuts in order to make a product for less.

This has enabled Equilibrium to set itself apart even in the Functional Medicine community as a leader in the best ingredients used.

 

GMP Certified

Besides never compromising on using the highest quality ingredients available when formulating our nutritional supplements, I make sure that each batch is 3rd Party tested for contaminants like:

  • Heavy metals
  • Mold
  • Bacteria
  • Impurities
  • Standard dosages

This then allows me to be confident when consuming these products myself and knowing that the dosages are what is stated on the bottle.

Again, this leads to better user results and happier customers and wellness clients!

 

Consistency & Freshness

Another way in which the Equilibrium Nutrition supplement line sets itself apart as the leader in the industry is by always producing fresh orders every couple of months.

Our products do not sit in warehouses for over a year…

Instead we maintain freshness with smaller continuous batch orders along with climate controlled fulfillment centers.

This guarantees purity, freshness, and taste.

This is a difference you can both see and taste with every bottle!

At Equilibrium Nutrition we strive to provide the fastest and most convenient shipping available!

United States Orders & Shipping 

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International Orders & Shipping

  • We’re excited to now ship to the following countries:
    • Australia, Iceland, Spain, Austria, Ireland, Sweden, Belgium, Italy, Switzerland, Canada, Latvia, Taiwan, Denmark, Netherlands, Ukraine, France, New Zealand, United Kingdom, Germany, Norway, Vietnam, Greece, Philippines, Hong Kong, Romania, Hungary, and Singapore
  • International taxes, tariffs and value-added tax (VAT), along with shipping charges will be calculated into your final order total during Checkout. International taxes, tariffs, and value-added tax (VAT) costs are determined by each individual country. We have no control over these amounts and 100% of these costs are paid to the country. By collecting these funds up-front, your order will be expedited locally and delivered without interruption. You will not be required to pay any additional fees (no COD) at the time of order delivery.
  • Exact shipping charges are determined at the time of checkout based on the number of items, item type, weight and volume of all the items in the cart.
  • For more information about our international shipping policy click here

My "Empty Bottle" 100% Satisfaction Guarantee

Since I know you’re going to absolutely love and see & feel the difference by using the Equilibrium Nutrition supplement line I’ve formulated for my private practice, my family, and online community I'm happy to offer you my “Empty Bottle Guarantee!

This means if you don’t see or feel the results you were looking for, or just don’t believe this was the absolute best product in its class that you’ve ever used, simply ship back the empty bottles, within 60 days of your purchase, for 100% of your product purchase price (not including S&H).

My team and I firmly believe in putting our clients and customers first, and we only want the best for you in your wellness, weight loss & anti-aging goals!

100% Satisfaction Guaranteed

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Folat