Vitamin C is a water-soluble vitamin that boasts many benefits including boosting immune system function and antioxidant reserves, maintaining normal inflammatory balance, as well as promoting collagen formation to maintain healthy skin, ligaments, tendons and joints. It's considered essential to humans because we are unable to synthesize it naturally. Furthermore, exposure to smoke, pollution, radiation, heavy metals and high-stress lifestyles all increase the body's requirement for vitamin C, making dietary supplementation recommended.
VITAMIN C BENEFITS†
- Boosts Immune System Function and Antioxidant Reserves
- Maintains Normal Inflammatory Balance
- Promotes Collagen Formation
- Maintains Healthy Skin, Ligaments, Tendons and Joints
Research has shown vitamin C to have a strong relationship with cardiovascular health and that supplemental vitamin C intake supports this. (1) Furthermore, supplementation had a significant impact on maintaining healthy blood fats (2). In addition, cross-sectional studies have indicated that plasma vitamin C concentration helps maintain healthy blood pressure levels in both men and women. (2-4)
Immune Function & Antioxidant Support
Vitamin C supplementation has been studied for more than six decades for its role in supporting the body during immune challenges. It has been shown to stimulate both the production (5,6) and function (7) of white blood cells—your immune system guardians. Further, through its potent antioxidant functions, vitamin C has been shown to protect these cells from self-inflicted oxidative damage.
Research has shown the ascorbic acid form of vitamin C in high doses to be beneficial in supporting immune health. (8,9) Additionally, vitamin C has been found to mediate histamine responses.
Skin & Beauty Support
The antioxidant properties of vitamin C and its role in collagen synthesis have been shown to promote skin health. Specifically, research has found that its role in collagen formation makes it vital to maintaining skin, capillary, gum, joint and skeletal health.
Keratinocytes (cells that produce keratin) have a high capacity for transporting vitamin C which compensates for limited blood flow to the epidermis. (10, 11) Research has also shown that Vitamin C's role in normal tissue repair and recovery may include promoting keratinocyte differentiation (12, 13) which stimulates the formation of the epidermal barrier and re-establishes the stratum corneum, the outermost layer of the epidermis. (14) Furthermore, intakes of dietary vitamin C have been correlated with a decreased risk of dry skin. (15)
THE DANGERS OF VITAMIN C DEFICIENCY †
Vitamin C helps to get rid of free radicals that can impact cells and tissue, which means fewer triggers for inflammation in the body with abundance. While a true deficiency in vitamin C is rare, evidence suggests that many people have low levels. Adequate intake and retention is necessary to maintain healthy vitamin C status in the body.
Signs of deficiency include dry and splitting hair, bleeding gums, dry or scaly skin and easy bruising. Severe vitamin C deficiency is known as a condition called scurvy—albeit rare in the majority of today's population, current lifestyle factors raise the requirement for this vitamin.
Take 2 capsules or more per day or as recommended by your health care professional.
DOES NOT CONTAIN
Gluten, yeast, artificial colors and flavors.
Consult your healthcare professional prior to using this product if you are pregnant, nursing, taking medication(s) or have a medical condition.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
1. Knekt P, Ritz J, Pereira MA, et al. Antioxidant vitamins and coronary heart disease risk: a pooled analysis of 9 cohorts. Am J Clin Nutr. 2004;80(6):1508-1520.
2. Moran JP, Cohen L, Greene JM, et al. Plasma ascorbic acid concentrations relate inversely to blood pressure in human subjects. Am J Clin Nutr. 1993;57(2):213-217.
3. Block G, Jensen CD, Norkus EP, Hudes M, Crawford PB. Vitamin C in plasma is inversely related to blood pressure and change in blood pressure during the previous year in young Black and White women. Nutr J. 2008;7:35.
4. Myint PK, Luben RN, Wareham NJ, Khaw KT. Association between plasma vitamin C concentrations and blood pressure in the European prospective investigation into cancer-Norfolk population-based study. Hypertension. 2011;58(3):372-379.
5. Prinz W, Bortz R, Bregin B, Hersch M. The effect of ascorbic acid supplementation on some parameters of the human immunological defence system. Int J Vitam Nutr Res. 1977;47(3):248-257.
6. Jariwalla RJ, Harakeh S. Antiviral and immunomodulatory activities of ascorbic acid. In: Harris JR (ed). Subcellular Biochemistry. Vol. 25. Ascorbic Acid: Biochemistry and Biomedical Cell Biology. New York: Plenum Press; 1996:215- 231.
7. Anderson R, Oosthuizen R, Maritz R, Theron A, Van Rensburg AJ. The effects of increasing weekly doses of ascorbate on certain cellular and humoral immune functions in normal volunteers. Am J Clin Nutr. 1980;33(1):71-76.
8. Kim Y, Kim H, Bae S, et al. Vitamin C Is an Essential Factor on the Anti-viral Immune Responses through the Production of Interferon-α/β at the Initial Stage of Influenza A Virus (H3N2) Infection. Immune Netw. 2013;13(2):70–74. doi:10.4110/in.2013.13.2.70
9. Gonzalez MJ et al (2018) High Dose Vitamin C and Influenza: A Case Report. J Orthomol Med. 33(3)
10. Steiling H, Longet K, Moodycliffe A, et al. Sodium-dependent vitamin C transporter isoforms in skin: Distribution, kinetics, and effect of UVB-induced oxidative stress. Free Radic Biol Med 2007;43:752-762.
11. Kang JS, Kim HN, Jung da J, et al. Regulation of UVB-induced IL-8 and MCP-1 production in skin keratinocytes by increasing vitamin C uptake via the redistribution of SVCT-1 from the cytosol to the membrane. J Invest Dermatol 2007;127:698-706.
12. Duarte TL, Cooke MS, Jones GD. Gene expression profiling reveals new protective roles for vitamin C in human skin cells. Free Radic Biol Med 2009;46:78-87.
13. Savini I, Catani MV, Rossi A, Duranti G, Melino G, Avigliano L. Characterization of keratinocyte differentiation induced by ascorbic acid: protein kinase C involvement and vitamin C homeostasis. J Invest Dermatol 2002;118:372-379.
14. From: http://lpi.oregonstate.edu/infocenter/vitamins/vitaminC/. Accessed 1-28-14.
15. Cosgrove MC, Franco OH, Granger SP, Murray PG, Mayes AE. Dietary nutrient intakes and skin-aging appearance among middle-aged American women. Am J Clin Nutr 2007;86:1225-1231.